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Archives: News

  • Innovations in Biotechnology and Medical Sciences

    Could Pythons be a Protein alternative?

    Why in the News?

    • In the farmlands of central Thailand, thousands of pythons are raised in a warehouse for their diamond-patterned skins, which are sold to high-end European fashion houses.
      • Some scientists and industry insiders believe the true value of these snakes lies in their meat.

    Python Farming in Asia

    • Researchers estimate that China and Vietnam alone have at least 4,000 python farms, producing several million snakes primarily for the fashion industry.
    • A study published in Nature highlighted python farming as a flexible and efficient response to global food insecurity.

    Benefits of Python Farming

    • Pythons can survive for months without food or water and maintain their condition.
    • They were fed waste chicken and wild-caught rodents, offering a more efficient feed-to-meat ratio than poultry, beef, and even crickets.
    • Female pythons can lay between 50 and 100 eggs annually, leading to rapid reproduction.

    Advantages of Python Meat

    • Pythons offer a more efficient feed-to-meat ratio than poultry, beef, and even crickets.
    • They can survive without food and water for months without losing condition.
    • Python meat has a chicken-like texture and is low in saturated fats.
    • It could provide a sustainable protein source with a lower environmental impact compared to traditional meat.

    Challenges and Market Acceptance

    • Despite the advantages, the market is limited for python meat.
    • Python farmers struggle to convince people to consume snake meat, resulting in most of it being discarded or sold to fish farms.

    Environmental Impact of Traditional Meat

    • The UN’s IPCC notes that meat from grazing animals has the greatest environmental impact.
    • The climate impact of traditional meat is significant, with beef identified as having the greatest environmental impact.
    • The UN and climate activists advocate for a more plant-based diet, but the demand for meat is expected to increase by 14% by 2032.
    • Drought and extreme weather are making traditional farming difficult in many parts of the world, increasing the need for alternative protein sources.
    • The paradox of rising meat demand and environmental concerns has spurred interest in alternatives like edible insects and lab-grown meats.

    Python Meat as an Alternative

    • Protein-energy malnutrition caused nearly 190,000 deaths globally in 2021, emphasizing the urgent need for protein sources in many parts of the world.
    • Python meat could help address this issue, offering a sustainable and efficient alternative.

     

    PYQ:

    [2018] How far do you agree with the view that the focus on lack of availability of food as the main cause of hunger takes the attention away from ineffective human development policies in India?

  • How the Peace Deal in Colombia has affected its Cocaine Industry?

    Why in the News?

    Colombia, the global center of the cocaine industry, is undergoing significant changes due to domestic and global forces.

    Recent Changes: Disruption in Cocaine Trade

    • Colombia, the global center of the cocaine industry, is undergoing significant changes due to domestic and global forces.
    • Two years ago, drug traffickers who buy coca paste stopped showing up.
    • This sudden halt left the villagers without income, leading to food shortages and exodus in search of jobs.
    • The population of Cano Cabra shrunk from 200 to 40 people.
    • This pattern has repeated in communities across Colombia where coca is the only source of income.

    About the FARC Peace Deal

    • It refers to the agreement reached between the Colombian government and the Revolutionary Armed Forces of Colombia (FARC) to end decades of conflict. It is a significant milestone in Colombia’s efforts to achieve lasting peace and stability.
    • FARC is a Marxist-Leninist guerrilla group founded in 1964 that waged an armed struggle against the Colombian government for over five decades.
    • The conflict resulted in over 220,000 deaths and the displacement of millions of people, making it one of the longest-running conflicts in Latin America.
    • A peace deal was signed on November 24, 2016, and subsequently ratified by the Colombian Congress.

    How does the peace deal impact Columbia?

    • The FARC financed its war through cocaine, relying on farmers to provide coca leaves.
    • After the FARC left the cocaine industry, smaller criminal groups took over, adopting a new economic model.
    • These groups buy large quantities of coca from fewer farmers and limit operations to border regions for easier drug transport.
    • The shift in the drug trade has left the communities economically devastated.

    Cocaine Production in Latin America:

    • Pablo Escobar the famous drug lord and the leader of the Medellín Cartel was a Colombian.
    • Ecuador has become a top cocaine exporter, and coca cultivation has increased in Peru and Central America.
    • These changes have pushed global cocaine production to record highs.
    • While cocaine consumption has reduced in the United States, it is growing in Europe and Latin America and emerging in Asia.

    Implications on India:

    • Changes in the Colombian cocaine industry may alter global drug trafficking routes.
    • India, as part of the global drug trade network, could see changes in the routes used to smuggle cocaine into the country.
    • Increased cocaine production globally could lead to a higher availability of the drug in India.
    • This could result in an increase in drug trafficking activities within the country visible in increased seizures in major cities like Pune.
    • Higher availability of cocaine could lead to an increase in drug abuse cases in India.

    PYQ:

    [2018] India’s proximity to the two of the world’s biggest illicit opium-growing states has enhanced her internal security concerns. Explain the linkages between drug trafficking and other illicit activities such as gunrunning, money laundering and human trafficking. What counter-measures should be taken to prevent the same?

  • Government Budgets

    Union Govt. eases Procurement Rules for Scientific Research Goods

    Why in the News?

    • The Finance Ministry has announced new rules under the General Finance Rules (GFR) to give scientific Ministries more flexibility in importing and buying research equipment.
      • These changes address scientists’ concerns about strict rules have slowed down research.

    Changes introduced in GFR

    • The limit for buying goods without needing a tender has been raised from ₹25,000 to ₹1,00,000.
    • For goods priced between ₹25,000 and ₹250,000, a committee of three members must check the market for the best value and quality.
    • This limit has been raised from ₹1,00,000 to ₹10,00,000.

    Note: These changes only apply if the goods are NOT available on the Government e-Marketplace (GeM).

    What are General Finance Rules (GFR)?

    • The General Finance Rules (GFR) are a set of rules issued by the Government of India to regulate financial matters in public administration.
    • They provide a framework for financial management, ensuring accountability, transparency, and efficiency in the use of public funds.
    • The GFR were first issued in 1947, post-independence.
    • The rules have been revised multiple times, with significant updates in 1963, 2005, and the latest in 2017.
    • The GFR applies to all central government departments, ministries, and organizations funded by the government.

    Key Provisions:

    • General System of Financial Management: Guidelines on budgeting, accounting, and auditing.
    • Procurement of Goods and Services: Rules for procurement, emphasizing transparency and competition.
    • Contract Management: Procedures for awarding, managing, and terminating contracts.
    • Inventory Management: Guidelines for managing government inventories and assets.
    • Grants-in-Aid: Procedures for providing grants to institutions and individuals.

    Major Highlights:

    • Emphasis on e-procurement to enhance transparency and efficiency.
    • Use of the Government e-Marketplace (GeM) for procurement of common use goods and services.
    • Requirement for performance security in government contracts to ensure compliance and reduce risk.
    • Strengthening of internal controls and audit mechanisms to ensure compliance with rules and regulations.

    Back2Basics: Government e-Marketplace (GeM)  

    • The GeM is a one-stop National Public Procurement Portal to facilitate online procurement of common use Goods & Services required by various Government Departments / Organizations / PSUs.
    • It was launched in 2016 by the Ministry of Commerce and Industry.
    • It was developed by the Directorate General of Supplies and Disposals (under MCI) with technical support from the National E-Governance Division (MEITy).
  • Electoral Reforms In India

    ECI’s technical SOP for EVM verification is out: why verify and how? 

    Why in the News?

    The ECI released a technical Standard Operating Procedure (SOP) on July 16 for verifying burnt memory in EVMs and VVPATs, following an April Supreme Court verdict.

    What is the Burnt Memory of EVM?

    • “Burnt memory” in Electronic Voting Machines (EVMs) refers to the firmware or software program permanently written onto the microcontroller’s memory during the manufacturing process.
    • This memory controls the EVM’s operations, and “burnt” implies it is fixed and cannot be altered or reprogrammed easily.

    What was the case before the Supreme Court, and what did it order?  

    Case Before the Supreme Court:

    • The Supreme Court was hearing a challenge to the reliability of Electronic Voting Machines (EVMs). The judgment was delivered on April 26, 2024, during the Lok Sabha election.
    • The Supreme Court upheld the EVM-VVPAT system and rejected the plea for a return to paper ballots and for 100% counting of VVPAT slips.
    • The court directed the Election Commission of India (ECI) to allow second and third-placed candidates to seek verification of burnt memories of EVMs and VVPATs of up to 5% of machines in an Assembly constituency or an Assembly segment of a Lok Sabha constituency.

    Court’s Orders:

    • The burnt memory/microcontroller in 5% of the EVMs (control unit, ballot unit, and VVPAT) per assembly constituency/assembly segment of a parliamentary constituency shall be checked and verified for tampering or modification.
    • Candidates who are at Sl. No. 2 or Sl. No. 3 behind the highest polled candidate can request verification in writing.
    • Candidates or their representatives have the option to be present during the verification process. Requests for verification must be made within seven days of the declaration of the result.
    • The actual cost or expenses for the verification will be notified by the ECI, and the candidate requesting the verification will bear the expenses. These expenses will be refunded if tampering is found.

    What is the process to be followed for the verification of EVMs and VVPATs? 

    Technical SOP by ECI:

    • Mock Poll: A mock poll of up to 1,400 votes per machine will be conducted in the presence of candidates or their representatives.
    • Result Comparison: If the results of the machines and VVPAT slips match, it will be concluded that the burnt memory or microcontrollers have not been tampered with.
    • Selection of Machines: Candidates can select the polling stations, EVMs, BUs, CUs, and VVPATs they want checked.
    • Verification Team: Trained engineers from the EVM manufacturers, Bharat Electronics Ltd (BEL) and Electronics Corporation of India Ltd (ECIL) will perform the checks.
    • Technical Methods: Various technical methods will be used to verify the fidelity of firmware burnt into a microcontroller through a public process.

    When will this process of checking start?

    • Preliminary Step: Verification will commence after it is confirmed by the High Courts of the respective states that no Election Petitions have been filed regarding the constituencies in question.
    • Election Petitions: Petitions challenging the election outcome can be filed within 45 days of the results being declared. Since the results were announced on June 4, petitions can be filed until July 19.
    • Applications Received: Eleven applications cover 118 polling stations or sets of EVMs and VVPATs. Applications have been received from candidates from BJP, Congress, DMDK, and YSRCP.

    Way forward: 

    • Enhanced Transparency and Confidence: Conduct regular and public verification processes of EVMs and VVPATs with involvement from political parties and independent observers to build public trust and confidence in the electoral system.
    • Technological Upgradation and Training: Invest in upgrading EVM technology and provide comprehensive training for election officials and engineers to ensure efficient and accurate verification and operation of voting machines.
  • Telecom and Postal Sector – Spectrum Allocation, Call Drops, Predatory Pricing, etc

    ‘Telecom sector awaits next frontier in communications via policy reform’  

    Why in the News?

    The telecom industry has proposed several policy recommendations to the Ministry of Communications that are essential to realize the Government’s vision of promoting digital empowerment and inclusivity.

    Present global status of the Indian market: 

    • Digital Connectivity Advancements: India has made significant strides in digital connectivity, positioning itself as the third-largest digitized country globally, following the USA and China.
    • Telecommunications Infrastructure: The telecommunications infrastructure in India serves as a cornerstone for digital transformation, facilitating connectivity across various devices and applications, thereby contributing to higher standards of living and economic growth.
    • Policy Reforms: Ambitious policy reforms have been implemented to elevate India’s status as a leading digital economy. These reforms aim at fostering digital empowerment and inclusivity, crucial for sustaining growth and competitiveness in the global market.

    Recommendations submitted by the telecom industry   

    • Reduction in Levy and Tax Burden:
      • Abolishment of the USOF (Universal Service Obligation Fund) levy because of  imposes a burden on telecom service providers (TSPs), diverting resources that could be invested in newer technologies such as 5G and network upgrades
        • USOF is the pool of funds generated by 5% Universal Service Levy that is charged upon all the telecom fund operators on their Adjusted Gross Revenue (AGR).
      • Reduction of the license fee from 3% to 1%.
      • Clarity in the definition of Gross Revenue (GR) to exclude non-telecom activities from tax calculations.
    • Exemption and Duty Reductions:
      • Exemption of Service Tax on additional Adjusted Gross Revenue (AGR) liabilities is demanded because it is crucial for the recovery of the industry’s financial health and ensuring efficient 5G rollout.
        • AGR has resulted in massive dues of over ₹1.5 lakh crore that telecom companies like Bharti Airtel, Vodafone Idea, and others have to pay.
      • Reduction of Customs Duty to zero for telecom manufacturing, with gradual increases for 4G and 5G products.
      • Urgency in renewing Customs Duty exemptions for submarine cable vessels to prevent future cost increases.
    • Spectrum Allocation:
      • Prioritization of 6 GHz spectrum for 5G deployment in India.
      • Strategic planning of 6 GHz spectrum for future 6G technologies, aiming at enhancing network quality, coverage, and supporting a range of advanced applications like telemedicine and smart cities.
    • Telecommunications Act 2023:
      • Introduction of the Telecommunications Act 2023, addressing critical issues such as Right of Way (RoW) for telecom infrastructure.
      • Standardization of RoW rules across states, simplification of licensing processes, and delinking telecom infrastructure from property taxes to facilitate faster deployment of 5G services.
    • Implementation of Reforms:
      • Emphasis on the swift implementation of regulatory reforms to minimize bureaucratic delays and operational hurdles.
      • Creation of a conducive environment for telecom investments by ensuring clarity and uniformity in RoW regulations, thereby improving the Ease of Doing Business (EoDB) in the sector.

    Conclusion: The Government should prioritize the swift implementation of proposed policy reforms, including the reduction of levies and taxes, clarity in revenue definitions, and spectrum allocation for 5G and future 6G technologies. Timely execution will bolster investor confidence, accelerate infrastructure development, and enhance digital connectivity nationwide.

    Mains PYQ:

    Q Cyber warfare is considered by some defence analysts to be a larger threat than even Al Qaeda or terrorism. What do you understand by Cyberwarfare? Outline the cyber threats which India is vulnerable to and bring out the state of the country’s preparedness to deal with the same. (2013)

  • Innovations in Sciences, IT, Computers, Robotics and Nanotechnology

    As thoughts become digitised, who will protect our Neurorights? 

    Why in the News?

    Many researchers anticipate the imminent development of wearable EEGs capable of enhancing human cognitive functions directly.

    • Elon Musk’s Neuralink has also sparked optimism by exploring brain-computer interfaces to potentially restore lost functions in physically impaired individuals.
    • Neuralink is a company founded by Elon Musk in 2016 that’s developing a brain-computer interface called “the Link,” which is a surgically embedded neural-chip implant designed to decode and stimulate brain activity.
    • Neuralink implanted its first device in a patient’s brain in January 2024.

    What is EEG?

    EEGs refer to electroencephalograms, which are devices used to record electrical activity in the brain. These devices are valuable in neuroscience for monitoring brain functions and diagnosing various neurological conditions.

    What is Neuroscience?

    Neuroscience is the scientific study of the nervous system, which includes the brain, spinal cord, and peripheral nerves. It is a multidisciplinary field that combines various approaches to understand the structure, function, and disorders of the nervous system.

    What is Neuro data?

    Neuro-data refers to data related to the nervous system, particularly the brain. It encompasses various types of data collected through neuroscience research and clinical studies.

    Significance of Neurodata:

    • Medical Advancements: It has the potential to provide precise diagnosis and personalized treatment of neurological disorders. It facilitates the continuous monitoring of brain health and early detection of abnormalities.
    • Technological Innovation: It supports the development of brain-computer interfaces (BCIs) and wearable neurodevices. It would enhance rehabilitation options for individuals with neurological impairments.
    • Research and Insights: It can provide data for studying brain functions, cognition, and behaviour. It fuels advancements in neuroscience, leading to new therapies and interventions.

    What are your neurorights?

    • Right to Mental Privacy: Individuals have the right to privacy concerning their neural activities and cognitive processes. This includes protection against unauthorized access to neural data and ensuring confidentiality in the use of neurotechnologies.
    • Right to Neurological Integrity: Individuals possess the right to autonomy over their neurological functions and activities. This entails the freedom from undue manipulation or coercion through neurotechnological interventions, ensuring that such technologies respect and preserve individuals’ neurological integrity.

    What is Neuroethics?

    Neuroethics is a field that addresses the ethical, legal, and social implications of advancements in neuroscience and neurotechnologies. It aims to ensure that the development and application of these technologies benefit humanity while minimising harm.

     

    The digitisation of neuro-data raises great opportunities as well as concerns  

    • Opportunities:

      • Enhanced Cognitive Assistance: Wearable EEGs and other neurotech devices can directly aid cognitive functions. For example, Brain-computer interfaces (BCIs) like Neuralink could help physically impaired individuals restore lost functions.
      • Medical Advancements: It provides Real-time health monitoring and personalized healthcare options. For example, Improved diagnosis and treatment of brain disorders through detailed neuro-data.
      • Commercial and Research Value: It provides Valuable insights for neuromarketing to understand and influence consumer behaviour.
      • Integration with Daily Life: It can be used in daily life by using Smartwatches and apps that can track physiological activities and emotions, integrating neurotech into everyday activities.
    • Concerns:

      • Surveillance Risks: It has a potential misuse of neuro data for monitoring by employers, governments, and private companies.
      • Privacy and Security: It may threaten mental privacy and autonomy with the collection and analysis of sensitive neuro data.
      • Ethical and Legal Challenges: It has the potential for ethical dilemmas in mental privacy, consent, and the use of neurotech in various societal contexts.
      • Impact on Individual Rights: The right to think freely and safeguard one’s mental state from monitoring could be compromised. For example, Digitized health data’s commercial value could lead to exploitation and loss of personal control.

    Initiatives related to neuroethics: 

    • Institutional Efforts:
      • U.S. Presidential Commission on Bioethics: In 2015, it published the ‘Gray Matters’ report, addressing cognitive enhancement, consent capacity, and the legal implications of neuroscience.
    • Global Initiatives:
      • OECD Recommendations: In 2019, the OECD recommended principles such as safeguarding personal brain data and monitoring potential misuse of neurotechnologies.
      • UNESCO’s Concerns: In 2022, UNESCO highlighted issues related to human identity, freedom of thought, and privacy, emphasizing the risks of unauthorized access to neural data.
    • Research and Training:
      • Institute of Neuroethics: In 2023, researchers emphasized the need for proactive consideration of the implications of scientific advances and incorporating ethics into research training.

    Conclusion: Governments and international bodies should collaborate to create robust regulations that govern the collection, use, and sharing of neuro data. These regulations should ensure that neurotechnologies are used ethically, protecting mental privacy, consent, and individual rights.

    Mains PYQ: 

    Q Discuss the advantages and security implications of cloud hosting of servers vis-a-vis in-house machine-based hosting for government business. (2015)

  • Child Rights – POSCO, Child Labour Laws, NAPC, etc.

    Trying juveniles as adults is not the answer  

    Why in the News?

    In May, a speeding car, allegedly driven by a teenager, resulted in the deaths of two young techies in Pune.

    • The Juvenile Justice Board (JJB) initially granted the minor bail on conditions like writing a 300-word essay on road safety. This decision sparked public outrage and criticism from the Maharashtra Deputy CM.
    • Later, the JJB canceled the minor’s bail and sent him to an observation home, which was again challenged in the Bombay High Court.
    • The Bombay High Court eventually ordered the release of the minor, stating that the JJB’s remand order was illegal and that the minor should be in the care of his paternal aunt as per the Juvenile Justice Act.

    What were the provisions led under the previous Juvenile Justice (Care and Protection of Children) Act of 2015?

    Definitions:
    • Section 2 defines a “child” as a person below the age of 18 years.
    • Section 2(13) defines “children in conflict with law” as those who are alleged or found to have committed an offence.
    • Section 2(14) defines “children in need of care and protection” as those meeting certain criteria, such as being homeless, engaged in illegal labour, victims of abuse, etc.
    Juvenile Justice Boards (JJBs):
    • Section 4 mandates the establishment of Juvenile Justice Boards in each district.
    • Section 4(2) states that the JJBs shall comprise a Metropolitan Magistrate or a Judicial Magistrate of the First Class and two social workers.
    • Section 8 outlines the powers and functions of the JJBs in handling cases related to children in conflict with the law.
    Child Welfare Committees (CWCs):
    • Section 27 requires the establishment of Child Welfare Committees in each district.
    • Section 28 defines the composition and functions of the CWCs in the care, protection, treatment, development, and rehabilitation of children in need of care and protection.
    Adoption Procedures:
    • Chapter VIII (Sections 56-65) provides a comprehensive adoption regime, including the establishment of the Central Adoption Resource Authority (CARA).
    • Sections 56-65 outline the adoption procedures and ensure transparency and accountability.
    Rehabilitation and Social Reintegration: Section 39 emphasizes the rehabilitation and social reintegration of children in conflict with the law through various measures, including counseling, education, skill development, and community-based programs.
    Preliminary Assessment for Heinous Offences: Section 15 mandates a preliminary assessment by the JJB to determine if a child in the age group of 16-18 years accused of committing a heinous offence should be tried as an adult.
    Children’s Court: Section 19 provides for the establishment of a Children’s Court to try children in the age group of 16-18 years accused of committing heinous offences.
    Mandatory Reporting: Section 19(1) makes it mandatory to report the presence of a child in need of care and protection to the authorities, and failure to do so is a punishable offence.
    Registration of Child Care Institutions: Section 41 requires all childcare institutions, whether run by the government or NGOs, to be registered within six months of the commencement of the Act.
    Penalties: Chapter XI (Sections 75-85) prescribes penalties for various offences, including the non-registration of childcare institutions and the sale and procurement of children.

    Amendment in 2021 

    • Empowering District Magistrates: The amendment authorized District Magistrates, including Additional District Magistrates, to issue adoption orders under Section 61 to ensure speedy disposal of cases and enhance accountability.
    • Strengthening Child Welfare Committees (CWCs): The eligibility parameters for the appointment of CWC members were redefined, and criteria for disqualification were introduced under Section 28 to ensure that only competent and capable individuals were appointed.
    • Categorization of Offences: The amendment categorized offences where the maximum sentence is more than 7 years imprisonment but no minimum sentence is prescribed or the minimum sentence is less than 7 years as “serious offences” under Section 2(54).
    • Addressing Implementation Challenges: The amendment introduced changes to remove difficulties arising in the interpretation of various provisions of the Act and to clarify the scope of certain provisions.

    Need for Accountability:

    • Promoting Justice and Fairness: Accountability ensures that juvenile offenders are held responsible for their actions in a manner that aligns with principles of justice and fairness.
    • Preventing Recidivism and Ensuring Rehabilitation: Holding juvenile offenders accountable helps in addressing underlying issues that contribute to their offending behaviour.
    • Maintaining Public Confidence and Trust: Accountability in the juvenile justice system enhances public confidence in the legal process and ensures transparency in decision-making.

    Conclusion: Implement comprehensive rehabilitation programs that are tailored to the individual needs of juvenile offenders, focusing on mental health support, educational opportunities, vocational training, and family reintegration.

    Mains PYQ: 

    Q Examine the main provisions of the National Child Policy and throw light on the status of its implementation. (2016)

  • Global Geological And Climatic Events

    Last Universal Common Ancestor (LUCA)

    Why in the News?

    • The origin of life on Earth remains one of the world’s most enduring mysteries.
      • Numerous competing theories exist, but none have conclusive proof.
      • A significant concept in understanding the origin of life is the Last Universal Common Ancestor (LUCA).

    What is the Last Universal Common Ancestor (LUCA)?

    • Researchers believe that all life forms— the Bacteria, the Archaea, and the Eukarya —originated from a single cell known as the last universal common ancestor (LUCA).
    • It is suggested to have been a “cellular organism that had a lipid bilayer and used DNA, RNA, and protein“.
    • There is a lack of clarity about direct fossil evidence of LUCA.
    • However, the shared features of modern genomes provide significant insights into this ancient ancestor.

    LUCA and the Molecular Clock:  

    • The molecular clock theory was proposed by molecular biologist Emile Zuckerkandl and biochemist Linus Pauling in the 1960s and later refined by biologist Motoo Kimura.
    • The theory allows scientists to reconstruct the evolutionary timeline.
    • According to the theory, the rate at which mutations are added or removed from a population’s genome is proportional to the rate of acquiring new mutations, which is constant.
    • By calibrating the molecular clock with known events, such as the emergence of the first mammals or the age of certain fossils, researchers can estimate the time between evolutionary events.

    Recent Research Findings on LUCA’s Age and Genome

    • Researchers at the University of Bristol and Exeter estimate that LUCA originated around 4.2 billion years ago, nearly 1 billion years earlier than previously thought. 
      • They obtained evidence from the 3.3 km deep Candelabra’ hydrothermal vent on the Mid-Atlantic Ridge.
    • LUCA had a small genome of about 2.5 million bases encoding 2,600 proteins, sufficient for survival in a unique niche.
    • Its metabolites may have created a secondary ecosystem for other microbes.
    • The presence of immunity genes in LUCA suggests it had to defend against viruses.

    Evidence Verification using Miller-Urey Experiment

    • In 1952, Stanley Miller and Harold Urey conducted an experiment at the University of Chicago, simulating lightning strikes on a mixture of methane, ammonia, and water, which resulted in the formation of amino acids.
    • This demonstrated that complex organic compounds could arise from inorganic compounds under the right conditions.

    Which is older: LUCA or fossils?

    • LUCA’s estimated origin at 4.2 billion years predates the earliest fossil records by almost 1 billion years.
    • Fossil records from the Pilbara Craton in Australia suggest life emerged around 3.4 billion years ago, but the study pushes this date back.

    Alternative Theories: 

    (1) Extraterrestrial Origin

    • Another prominent theory suggests that meteorites from space could have brought the building blocks of life to Earth.
    • This theory is supported by various discoveries.
    • In August 2019, French and Italian scientists reported finding 3.3 billion-year-old extraterrestrial organic material.
    • Japan’s Hayabusa 2 mission to the asteroid Ryugu detected more than 20 amino acids, further supporting the possibility of an extraterrestrial origin for the building blocks of life.

    (2) Oparin-Haldane Hypothesis

    • In the 1920s, Alexander Oparin and J.B.S. Haldane independently proposed theories regarding the origin of life.
    • They suggested that life originated from a “primordial soup” in a prebiotic environment on the young Earth.
    • This concept is now known as the Oparin-Haldane hypothesis.

     

    PYQ:

    [2012] Which one of the following sets of elements was primarily responsible for the origin of life on the Earth?

    (a) Hydrogen, Oxygen, Sodium

    (b) Carbon, Hydrogen, Nitrogen

    (c) Oxygen, Calcium, Phosphorus

    (d) Carbon, Hydrogen, Potassium

  • Festivals, Dances, Theatre, Literature, Art in News

    [pib] World Heritage Young Professionals Forum, 2024

    Why in the News?

    • India is hosting the UNESCO’s World Heritage Committee meeting for the first time in New Delhi.
      • Theme: “World Heritage in the 21st Century: Building Capacities and Exploring Opportunities for Youth.”

    About the World Heritage Young Professional Forum

    • The World Heritage Young Professionals Forum is an initiative by UNESCO to engage young professionals in the field of heritage conservation.
    • The first World Heritage Young Professionals Forum was organized in 1995.
    • The primary aim is to engage young professionals in heritage conservation and management through capacity building, networking, and awareness-raising.

    Back2Basics: UNESCO World Heritage Sites

    Description
    UNESCO World Heritage Sites Landmarks or areas selected by UNESCO for their cultural, historical, scientific, or other significant value, legally protected by international treaties.
    Importance World Heritage Sites represent collective and preservative interests of humanity, signifying remarkable accomplishments and intellectual history.
    Selection Criteria Sites must be already-classified landmarks, unique and significant culturally or physically, such as ancient ruins, historical structures, cities, monuments, etc.
    Conservation World Heritage Sites require practical conservation to protect them from risks like trespassing, uncontrolled access, or administrative negligence.
    World Heritage Committee Selects and monitors World Heritage Sites, manages the World Heritage Fund, and provides financial assistance. Composed of 21 states parties elected for a four-year term.
    Membership India is not a member of the World Heritage Committee.

     

    PYQ:

    [2014] Consider the following international agreements:

    1. The International Treaty on Plant Genetic Resources for Food and Agriculture
    2. The United Nations Convention to Combat Desertification
    3. The World Heritage Convention

    Which of the above has / have a bearing on the biodiversity?

    (a) 1 and 2 only

    (b) 3 only

    (c) 1 and 3 only

    (d) 1, 2 and 3

  • Minority Issues – SC, ST, Dalits, OBC, Reservations, etc.

    Karnataka State Employment of Local Candidates in the Industries, Factories and Other Establishments Bill, 2024

    Why in the News?

    The Karnataka Cabinet has approved a bill mandating that industries, factories, and other establishments appoint local candidates in 50% of management positions and 75% in non-management positions.

    • The bill was cleared in a Cabinet meeting chaired by the Chief Minister.

    Key features of the Bill:

    • Definition of a Local Candidate:
      • Born in Karnataka
      • Domiciled in Karnataka for 15 years
      • Proficient in speaking, reading, and writing Kannada
      • Passed a required test by the nodal agency
    • Educational Requirements:
      • Must have a secondary school certificate with Kannada as a language, or
      • Pass a Kannada proficiency test specified by the nodal agency
    • Training and Relaxation Provisions:
      • Industries and establishments must train local candidates within three years if qualified locals are unavailable
      • Establishments can apply for relaxation if local candidates are insufficient
      • The government’s decision on relaxation applications is final
      • Local candidates must constitute at least 25% in management and 50% in non-management positions
      • Non-compliance penalties range from ₹10,000 to ₹25,000

    Do you know?

    • The Punjab and Haryana High Court earlier quashed the Haryana State Employment of Local Candidates Act, 2020, which mandated 75% reservation for state domiciles in the private sector jobs.
    • This decision was made because the State had overstepped its legislative authority and imposed undue restrictions on private employers.

    Background and Rationale:

    • Long-pending Demand:
      • The bill has been passed in response to longstanding demands for 100% job reservation for Kannadigas.
      • Earlier in July, Kannada organizations organized rallies in parts of the State, demanding immediate implementation of the Sarojini Mahishi Report.
    • Sarojini Mahishi Report:
      • The Sarojini Mahishi report, submitted in 1984 by Mahishi, former Union Minister and the first woman MP from Karnataka, included 58 recommendations.
      • The report recommended 100% reservation for locals in group C and D jobs in Central government departments and public sector undertakings (PSUs) in Karnataka.

    Reservation for Locals in Jobs: Constitutionality Check 

    Provision Potential Violation
    Article 14 Guarantees equality before the law and equal protection of the laws. Reservation for locals could create unequal opportunities for non-locals, violating the principle of equality.
    Article 15 Prohibits discrimination on grounds of religion, race, caste, sex, or place of birth. Reserving jobs for locals based on place of birth or domicile status may constitute discrimination against non-locals.
    Article 16 Ensures equality of opportunity for all citizens in matters relating to employment or appointment to any office under the State. Though it allows reservation for backward classes, it does not explicitly extend this provision to private employment, making mandatory quotas for locals potentially unconstitutional.
    Article 19 Guarantees the freedom to move freely throughout the territory of India. Imposing local reservations could restrict the free movement of people seeking employment opportunities across states, infringing upon their freedom of movement and residence.

     

    PYQ:

    [2017] One of the implications of equality in society is the absence of:

    (a) Privileges

    (b) Restraints

    (c) Competition

    (d) Ideology

  • Civil Aviation Sector – CA Policy 2016, UDAN, Open Skies, etc.

    India to host 2nd Asia Pacific Ministerial Conference on Civil Aviation

    Why in the News?

    • India will host the second Asia Pacific Ministerial Conference on Civil Aviation on September 11 and 12.
      • The conference will be jointly organised by the Indian government and the International Civil Aviation Organization (ICAO) APAC.

    About the International Civil Aviation Organization (ICAO)

    Details
    Establishment and Background
    • Founded on December 7, 1944, by the Chicago Convention on International Civil Aviation
    • Became a specialized agency of the United Nations in 1947
    • HQ: Montreal, Canada
    Objectives and Mission
    • Develop international standards and regulations for aviation safety, security, efficiency, and environmental protection
    • Promote safe and orderly growth of international air transport
    Structure and Governance
    • Assembly: Meets every three years, includes all member states
    • Council: Governing body with 36 elected member states
    • Secretariat: Led by the Secretary General, manages daily operations
    Membership
    • 193 member states as of 2024
    • Open to all states subscribing to Chicago Convention principles
    • India: Founding member, joined in 1944
    Functions and Responsibilities
    • Establish international standards and recommended practices (SARPs)
    • Conduct audits and monitor SARPs compliance
    • Provide technical assistance and capacity-building
    • Facilitate aviation data and statistics collection
    Key Areas of Focus
    • Safety: Enhance global aviation safety
    • Security: Strengthen aviation security measures
    • Efficiency: Promote efficient air navigation services
    • Environmental Protection: Address aviation’s environmental impact
    Significant Programs and Initiatives
    • Universal Safety Oversight Audit Programme (USOAP): Monitors safety oversight capabilities
    • Universal Security Audit Programme (USAP): Evaluates aviation security measures
    • Next Generation Aviation Professionals (NGAP): Addresses anticipated aviation professionals shortage
    • No Country Left Behind (NCLB): Assists states in implementing ICAO standards and policies
    Publications and Resources
    • Annexes to the Chicago Convention: SARPs across civil aviation domains
    • ICAO Journal: Quarterly publication
    • Global Aviation Safety Plan (GASP) and  Global Air Navigation Plan (GANP): Strategic documents for aviation safety and navigation improvements.
    Regional Offices Seven offices in Bangkok, Cairo, Dakar, Lima, Mexico City, Nairobi, and Paris
    Standards
    • Annex 1: Personnel Licensing
    • Annex 6: Operation of Aircraft
    • Annex 8: Airworthiness of Aircraft
    • Annex 17: Security
    • Annex 19: Safety Management
    Global Impact
    • Harmonizes international aviation policies and procedures
    • Contributes to safe, secure, and sustainable growth of global air transport

    About Asia Pacific Ministerial Conference on Civil Aviation

    • The conference aims to strengthen regional collaboration and develop a future-focused vision for the region, emphasizing innovation and safety.
    • The inaugural conference took place in February 2018 in Beijing.
    • 39 member states of the UN aviation safety body, the International Civil Aviation Organisation (ICAO), from the Asia Pacific region are expected to attend.
    • The conference focuses on making aviation travel sustainable, resilient, and adaptive to the changing needs of a globally interconnected community.
      • This region accounts for 33.41% of global flight departures, the highest of any region worldwide.
      • Passenger numbers are expected to increase from 4.5 billion this year to 11.5 billion by 2050.

    PYQ:

    [2014] International civil aviation laws provide all countries with complete and exclusive sovereignty over the airspace above their territory. What do you understand by ‘airspace’ What are the implications of these laws on the space above this airspace? Discuss the challenges which this poses and suggest ways to contain the threat.

  • ISRO Missions and Discoveries

    ISRO has a problem: many rockets, but too few satellites to launch 

    Why in the News? 

    After the ambitious Next Generation Launch Vehicle (NGLV) was finalized in June 2024, ISRO Chairman S. Somanath stated its launch capability exceeded demand threefold, highlighting a need for robust domestic market demand for launch vehicles.

    What is the present scenario of Satellites in India?   

    • India operates a diverse fleet of satellites with applications in Communications, Remote Sensing, Positioning, Navigation and Timing (PNT), Meteorology, Disaster Management, Space-based internet, Scientific missions, and Experimental missions.
    • India currently has four main launch vehicles: the Small Satellite Launch Vehicle (SSLV), the Polar Satellite Launch Vehicle (PSLV), the Geosynchronous Satellite Launch Vehicle (GSLV), and the Launch Vehicle Mark-III (LVM-3), capable of launching satellites up to four tonnes to geosynchronous orbit.
    • For satellites weighing more than four tonnes, India relies on foreign launch vehicles, such as Europe’s Ariane V and SpaceX’s Falcon 9, to meet its heavy payload requirements.
    • India has been actively involved in significant space missions like Chandrayaan 3 (a lunar mission) and Aditya L1 (a mission to study the Sun), showcasing its growing capabilities in space exploration.

    Existing Demand-Driven Model in India – Before and After       

    • Before (Supply-Driven Model)
        • The Indian Space Research Organisation (ISRO) primarily built and launched satellites based on its assessments and planned missions without waiting for specific customer demands.
        • After launching satellites, ISRO would then look for customers who needed the services provided by the satellites, which sometimes led to underutilization or delayed utilization of satellite capabilities.
        • The space sector was heavily government-controlled, with limited involvement and investment from private players
        • There was less emphasis on educating potential customers about the benefits and applications of space-based services, leading to lower demand from various sectors.
    • After 2020 (Demand-Driven Model)
      • The Space sector reforms 2019-2020 encouraged greater private sector participation, fostering innovation, competition, and commercialization in the Indian space industry.
      • Satellites are now built and launched based on confirmed customer demands, ensuring that each satellite has a predefined purpose and user base before it is sent into space.
      • The market demand for satellite services is validated and secured before the construction and launch phases, leading to better alignment of resources and higher utilization rates.

    Major Three Limitations Associated at Present Time:

    • Limited Launch Vehicle Capability: Currently, the Indian launch vehicles have restricted payload capacities, necessitating multiple launches for larger missions, increasing costs and complexity.
    • Demand-Supply Mismatch: Transitioning from a supply-driven to a demand-driven model faces challenges, including the need to educate potential customers and create a robust private sector ecosystem.
    • Economic and Technological Constraints: High costs of developing and maintaining launch vehicles and satellites, coupled with the early stages of implementing cost-effective reusable technologies, and insufficient infrastructure and investment.

    Way forward: 

    • Enhance Launch Vehicle Capacity: Invest in research and development to upgrade existing launch vehicles like GSLV and LVM-3 to increase payload capacity, reducing dependence on foreign launch providers.
    • Strengthen Market Engagement and Education: Expand outreach programs to educate potential customers across sectors about the benefits and applications of satellite-based services.
    • Promote Private Sector Participation: Facilitate a conducive regulatory environment to attract private investments and foster innovation in satellite manufacturing and launch services.

    Mains PYQ: 

    Q India has achieved remarkable successes in unmanned space missions including the Chandrayaan and Mars Orbiter Mission, but has not ventured into manned space missions. What are the main obstacles to launching a manned space mission, both in terms of technology and logistics? Examine critically. (UPSC IAS/2017)

  • Foreign Policy Watch: India-China

    China’s Communist Party begins ‘Third Plenum’ with focus on slowing economy       

    Why in the news? 

    China’s Communist Party commenced and formulated a strategy for achieving self-reliant economic growth amidst heightened National security concerns and restrictions on American technology access.

    What are the plenums of the Chinese Communist Party?

    The Chinese Communist Party holds a major congress twice a decade, where members of the Central Committee are elected. In between the party congresses, the Central Committee holds seven plenums attended by all its current members.

    The plenums are numbered from 1st to 7th, with each focusing on different aspects:

    • 1st, 2nd, and 7th plenums typically focus on power transitions between Central Committees.
    • 4th and 6th plenums generally center on party ideology.
    • 3rd plenums have historically focused on long-term economic reforms.
    • 5th plenums are associated with deliberations for the country’s five-year development plans.

    What are the major decisions taken at these meetings?   

    • Chinese govt is planning to take measures to restore and expand domestic consumption, focusing on sectors like automobiles, real estate, and services.
    • Reforms are also planned to transform the mechanisms of economic development by making the domestic market and technological innovation the main drivers of growth and emphasis on advancing the New Development Pattern adopted in the 14th Five-Year Plan (2021-2025)
    • Provisions that provided relaxation of restrictions on home purchases and funding curbs on property developers in some cities are incorporated to boost the struggling real estate market.
    • Focus on advancing science and technology sectors like Artificial Intelligence, Green Energy and Electric Vehicles under the “New Quality productive Forces” initiative

    What are the expected implications shortly for regional trade and politics?

    • Trade and Economic Relations: Policies discussed at plenums can impact China’s trade strategies on economic reforms, market regulations, and industrial policies could influence trade volumes, tariffs, and investment flows.
      • Changes in China’s economic policies could include shifts in investment patterns, and infrastructure projects linked to China’s Belt and Road Initiative.
    • Security Dynamics: Discussions on National security policies and Military strategies can impact regional security dynamics, especially India’s Arunachal Pradesh region influencing alliances, defense postures, and regional stability.

    Conclusion: The Indian Government needs to watch its ‘Neighbourhood First’ Policy very effectively keeping its stance assertive rather than passive this time.

    Mains PYQ: 

    Q China is using its economic relations and positive trade surplus as tools to develop potential military power status in Asia’, In the light of this statement, discuss its impact on India as her neighbor. (UPSC IAS/2017)

  • Parliament – Sessions, Procedures, Motions, Committees etc

    SC to look into the use of ‘Money Bills’ to pass laws   

    Why in the News? 

    CJI D.Y. Chandrachud has accepted the plea to list petitions challenging the passage of contentious legislation in Parliament as Money Bills.

    • This has given rise to the expectation that the matter could be heard and decided before Chandrachud demits office in November this year.

    Presently, the three key issues are referred to the 7-judge bench in the Supreme Court:

    • Amendments made post-2015, like the Prevention of Money Laundering Act (PMLA) through Money Bills, giving the Enforcement Directorate wide powers, were valid or not.
    • Whether the passage of the Finance Act of 2017 as a Money Bill to alter appointments to 19 key judicial tribunals was valid or not
    • In the Aadhaar case, the Supreme Court had in 2018 upheld the Aadhaar Act as a valid Money Bill.
      • However, in 2021, Justice D.Y. Chandrachud (who was then a part of the bench) had dissented, saying the larger questions on Money Bills should be decided first before reviewing the Aadhaar judgment.
    • Now, the current Chief Justice D.Y. Chandrachud has agreed to list the petitions challenging the use of the Money Bill route by the Centre to pass contentious amendments, indicating he will constitute a 7-judge Constitution Bench to hear this matter.

    What is a Money Bill?

    • A Money Bill is a specific type of financial legislation that exclusively deals with matters related to taxes, government revenues, or expenditures.
      • It is defined under Article 110 of the Indian Constitution.
    • Every Money Bill is a Finance Bill but every Financial Bill is not a Money Bill: A Financial Bill can cover a broader range of financial issues, whereas a Money Bill is specifically limited to the matters mentioned in Article 110 of the Constitution. Therefore, while every Money Bill is a Financial Bill, not every Financial Bill is a Money Bill.

    Key provisions of the Money Bill: 

    • Article 110(1)(a): Imposition, abolition, remission, alteration, or regulation of any tax
    • Article 110(1)(b): The regulation of borrowing by the government or giving of any guarantee by the government or the amendment of the law for any financial obligations undertaken by the government
    • Article 110(1)(c): Custody of the Consolidated Fund or the Contingency Fund of India, the payment of money into or the withdrawal of money from any such Fund. 
    • Article 110(1)(d): Appropriation of money out of the Consolidated Fund of India
    • Article 110(1)(e): Declaration of any expenditure to be expenditure charged on the Consolidated Fund of India or the increase of the amount of any such expenditure
    • Article 110(1)(f): Receipt of money on account of the Consolidated Fund of India or the public account of India or the custody or issue of such money or the audit of the accounts of the Union or of a State
    • Article 110(1)(g): Any matter incidental to any of the matters specified in sub-clauses (a) to (f).

    What are the present challenges associated with the Parliament?

    • Circumvention of the Rajya Sabha:  The government is accused of misusing the Money Bill provision to evade scrutiny of the Bill by the Rajya Sabha where it was numerically weaker as compared to the Lok Sabha where it enjoyed pre-eminence.
    • Contentious Amendments passed as the Money Bill: Aadhaar Act, 2016; amendments to the Prevention of Money Laundering Act, 2002; amendments to the Foreign Contributions Regulations Act, 2010; Finance Act, 2017 which brought about changes in the mode of appointment of judicial tribunals; electoral bonds scheme brought through Finance Act, 2017.
      • For example, the Finance Act of 2017, passed as a Money Bill, altered the appointment processes for judicial tribunals, which was seen as an attempt to extend executive control over these institutions.
      • The Supreme Court has been involved in multiple such cases questioning the classification of certain bills as Money Bills. For instance, the Rojer Mathew case and the Aadhaar case (K. Puttaswamy case)
    • Finality of the Speaker’s Decision: The Lok Sabha Speaker’s decision to certify a bill as a Money Bill has been contested. The judiciary has debated whether this decision is final or subject to judicial review.

    Way forward: 

    • Need for strengthening Judicial Oversight: Establish clear guidelines and criteria for the classification of bills as Money Bills, ensuring they strictly adhere to the provisions outlined in Article 110 of the Constitution.
    • Requires the Reinforcement of Legislative Procedures: Enhance the role of the Rajya Sabha in the legislative process by ensuring that all significant amendments, especially those affecting governance structures or individual rights, undergo thorough scrutiny in both houses of Parliament.

    Mains PYQ: 

    Q The Indian Constitution has provisions for holding joint session of the two houses of the Parliament. Enumerate the occasions when this would normally happen and also the occasions when it cannot, with reasons thereof. (UPSC IAS/2017)

  • Terrorism and Challenges Related To It

    What is Maharashtra’s new bill to combat Naxalism in urban areas?   

    Why in the News? 

    The Maharashtra state government has introduced a comprehensive new legislation – Maharashtra Special Public Security (MSPC) Bill, 2024,  to address the growing incidence of Naxalism in urban areas.

    • The Maharashtra government claims that Naxalism is no longer limited to remote rural areas, but has now spread its influence to urban centers through “frontal organizations”.
    • The government argues that existing laws like the Unlawful Activities Prevention Act (UAPA) and Maharashtra Control of Organised Crime Act are not sufficient to effectively control these urban Naxal organizations.

    Key provisions drafted under the MPSC Bill, 2024:

    Declaration of Unlawful Organizations The bill empowers the state government to declare any organization as “unlawful” under Section 3. 

    An advisory board of three qualified individuals (current/former/qualified High Court judges) will review such decisions as per Section 4.

    Definition of Unlawful Activities The bill defines “unlawful activities” in broad terms, including “activities threatening public order, peace, and tranquility” (Section 2(f)(i)), “interference with law administration and public servants” (Section 2(f)(ii)), and “encouraging disobedience to law and institutions” (Section 2(f)(iv)).
    Cognizable and Non-Bailable Offences All offences under this law will be cognizable and non-bailable, and will be investigated by a police officer not below the rank of a Sub-Inspector as per Section 9.
    Punishments
    • Members of Unlawful Organizations: Imprisonment up to 3 years and fines up to Rs 3 lakh (Section 10)
    • Non-members Contributing or Aiding Unlawful Organizations: Imprisonment up to 2 years and fines up to Rs 2 lakh (Section 11)
    • Management or Promotion of Unlawful Organizations: Imprisonment up to 3 years and fines up to Rs 3 lakh (Section 12)
    • Committing, Abetting, or Planning Unlawful Activities: Imprisonment up to 7 years and fines up to Rs 5 lakh (Section 13)
    Seizure and Forfeiture The District Magistrate or Commissioner of Police can notify and take possession of any place used for unlawful organization activities (Section 14). The government can also forfeit money and assets intended for unlawful organizations (Section 15).
    Legal Review An advisory board must review the declaration of unlawful organizations within six weeks and submit a report within three months (Section 4). The High Court can review government actions through revision petitions (Section 7).

     

    Why it is being seen as a threat to civil liberty:

    • Vague Definitions of Unlawful Activities: The bill defines “unlawful activities” in broad and vague terms, including “activities threatening public order, peace, and tranquility” and “encouraging disobedience to law and institutions” in Section 2(f)(i) and (iv).
    • Excessive Powers Granted to the State: The bill allows the state government to unilaterally declare an organization as “unlawful” without adequate judicial oversight in Section 3. It also empowers District Magistrates and Police Commissioners to grant permission for prosecution, bypassing the courts in Section 9.
    • Threat to Civil Liberties and Press Freedom: The bill’s broad provisions in Sections 2(f) and 8 could be used to criminalize activities such as reporting on administrative failures or the plight of citizens, as seen in other states with similar laws. This poses a threat to press freedom and the right to freedom of expression.
    • Lack of Transparency and Public Consultation: The bill was tabled hastily, with the draft not made available for public scrutiny and objections, as noted by civil society members.

    Potential for Misuse and Abuse: Given the vague definitions in Section 2(f) and excessive powers granted to the state in Sections 3, 8 and 9, the bill has a high potential for misuse and abuse against political opponents, activists, and journalists, turning Maharashtra into a “police state”.

    Way forward: 

    • Consultative Process: The Maharashtra government should engage in a consultative process with legal experts, civil society organizations, and stakeholders to refine the bill’s provisions, ensuring they align with constitutional principles and international human rights standards.
    • Safeguarding Rights: Introduce safeguards such as judicial oversight in the process of declaring organizations unlawful, ensuring that fundamental rights like freedom of expression and assembly are protected while addressing legitimate security concerns effectively.

    Mains PYQ: 

    Naxalism is a social, economic and developmental issue manifesting as a violent internal security threat. In this context, discuss the emerging issues and suggest a multilayered strategy to tackle the menace of Naxalism. (2022)

  • Innovations in Sciences, IT, Computers, Robotics and Nanotechnology

    Tirzepatide: the Weight-loss Drug nearing Approval in India

    Why in the News?

    • India’s apex drug regulator Central Drug Standard Control Organisation (CDSCO) gave preliminary approval to the drug Tirzepatide.
      • Tirzepatide is known to have assisted in weight control treatment among diabetic patients.

    About Central Drugs Standard Control Organisation (CDSCO): 

    • CDSCO is India’s national regulatory body for cosmetics, pharmaceuticals and medical devices.
    • It serves a similar function to the Food and Drug Administration (FDA) of the US or the European Medicines Agency of the European Union.
    • The Indian government has announced its plan to bring all medical devices, including implants and contraceptives under a review of the CDSCO.
    • Within the CDSCO, the Drug Controller General of India (DCGI) regulates pharmaceutical and medical devices and is positioned within the Ministry of Health and Family Welfare.
    • The DCGI is advised by the Drug Technical Advisory Board (DTAB) and the Drug Consultative Committee (DCC).

    Mandate and Responsibilities:

    • Drug Approval: CDSCO is responsible for the approval of new drugs and clinical trials.
    • Standards Enforcement: Ensures standards of drugs and medical devices through various acts such as the Drugs and Cosmetics Act, 1940.
    • Import and Export: Regulates the import and export of drugs and medical devices in India.
    • Licensing Authority: Issues licenses for the manufacture, sale, and distribution of drugs in India.
    • Surveillance: Conducts drug quality surveillance and monitors adverse drug reactions.

     

    Diabetes Drug for Weight Loss

    • In 2017, the US Food and Drug Administration (FDA) approved a drug called Ozempic for managing type 2 diabetes.
    • The active ingredient, semaglutide, was later noted for causing weight loss, which led to its off-label use for treating obesity.
    • This usage became popular on social media, influencing further developments.

    What is Tirzepatide?

    • Tirzepatide is the main component of Eli Lilly’s drugs, Mounjaro and Zepbound.
    • It’s important to note here that Mounjaro is the brand name for diabetes, while Zepbound is for weight loss.

    How does it work?

    There is a dual action involving two hormones:

    (1) Regulation of glucagon-like peptide-1 (GLP-1): 

    • GLP-1 is a hormone that regulates appetite and calorie intake through effects on the brain and digestive tract.
    • Both semaglutide and tirzepatide function as polypeptides that enhance the body’s levels of GLP-1.
    • The higher levels of GLP-1 trigger satiety, the feeling of fullness, reducing the desire to eat.

    (2) Regulation of Glucose-dependent Insulinotropic polypeptide (GIP):

    • Unlike semaglutide, tripeptide also increases levels of GIP, the other hormone involved.

    Promising Global Trials

    • Global clinical trials for tirzepatide (Zepbound) have shown significant results, with the highest dosage leading to an average weight loss of 20.9% over 72 weeks.
    • The approval in India is due on further post-marketing surveillance (Phase IV trials) to monitor the drug’s side effects and its effectiveness across India’s diverse population.

    Long-term side effects:

    • Cardiovascular risks like increased heart rate and potential blood pressure elevation.
    • Gastrointestinal effects include nausea, vomiting, diarrhoea, and constipation. Endocrine concerns involve thyroid C-cell tumours in MEN syndrome patients.
    • Other issues include kidney problems, eye complications, mental health impacts, and long-term risks like pancreatic enzyme elevation and gallbladder problems.

    Why under-consideration in India?

    • India has the world’s second-highest number of people with type 2 diabetes and high obesity rates.
    • A study in Lancet in 2023 estimated that 101 million people in India — 11.4 per cent of the country’s population — are living with diabetes.
    • As per the World Obesity Federation Atlas, around 11 per cent of Indian adults will be obese by 2034.
  • Civil Aviation Sector – CA Policy 2016, UDAN, Open Skies, etc.

    Uniform IGST Rate of 5% on Aircraft and Aircraft Engine Parts

    Why in the News?

    The government has implemented a uniform Integrated Goods and Services Tax (IGST) rate of 5% on all aircraft and aircraft engine parts.

    Background: 

    • Prior to the implementation of GST in 2017, the taxation of aircraft and aircraft parts was complex, with different central and state taxes being levied.
    • Under the pre-GST regime, aircraft parts attracted a range of taxes, including excise duty, VAT, and additional customs duties, leading to a cascading effect and higher costs for the aviation industry.

    IGST Harmonization for MRO Boost:

    • This move is aimed at boosting Maintenance, Repair, and Overhaul (MRO) activities in India.
    • Previously, GST rates on aircraft components varied between 5%, 12%, 18%, and 28%, causing several issues.

    MRO Industry in India

    • The Indian MRO industry is projected to become a $4 billion industry by 2030.
    • Currently, India represents only 1% of the global MRO market, which is worth US$45 billion.
    • The industry is divided into airframe maintenance, engine maintenance (50-55% of work value), components maintenance, and line maintenance (weekly checks).
    • Commercial airlines spend 13-15% of their revenues on maintenance, primarily outsourcing heavy maintenance.

    What is Integrated Goods and Services Tax (IGST)?

    • The IGST is a component of the GST system in India.
    • It is levied by the central government on:
    1. Inter-state /UT supply of goods and services;
    2. Imports of goods and services;
    3. Supply of goods and services to/by SEZ units;
    4. Deemed exports (certain transactions where goods supplied do not leave the country but are treated as exports under GST law).
    • IGST is calculated by adding the applicable Central GST (CGST) and State GST (SGST) rates.
    • One thing to remember in IGST is that the importing state gets the accrued benefit of taxes.

    Rationale for the Uniform 5% IGST Rate

    • Simplification of Tax Structure: A uniform 5% IGST rate on aircraft and engine parts simplifies tax compliance and eliminates classification complexities.
    • Cost Efficiency: A lower IGST rate reduces overall tax burden on aviation industry, enhancing affordability of aircraft acquisition and maintenance.
    • Global Alignment: Aligns India’s tax policy with global standards, fostering competitiveness and attractiveness for international aviation investments.
    • Promotion of Aviation Services: Encourages aircraft leasing and MRO activities, supporting India’s aspiration to become a hub for these services.

    PYQ:

    [2017] What is/are the most likely advantages of implementing ‘Goods and Services Tax (GST)’?

    1.  It will replace multiple taxes collected by multiple authorities and will thus create a single market in India.
    2. It will drastically reduce the ‘Current Account Deficit’ of India and will enable it to increase its foreign exchange reserves.
    3. It will enormously increase the growth and size of economy of India and will enable it to overtake China in the near future.

    Select the correct answer using the code given below:

    (a) 1 only
    (b) 2 and 3 only
    (c) 1 and 3 only
    (d) 1, 2 and 3

  • Innovation Ecosystem in India

    ICAR launches ‘One scientist, One product’ Scheme 

    Why in the News?

    • The Indian Council of Agricultural Research (ICAR) is set to launch its ‘One Scientist-One Product’ program. This initiative aims to enhance research in agriculture and animal husbandry.

    About the Indian Council of Agricultural Research (ICAR)

    • ICAR is an autonomous organisation under the Department of Agricultural Research and Education (DARE), Ministry of Agriculture and Farmers Welfare.
    • It is headquartered in New Delhi.
    • ICAR was formerly known as the Imperial Council of Agricultural Research.
    • It was established in 1929 as a registered society under the Societies Registration Act, 1860 on the basis of the report of the Royal Commission on Agriculture.

    Functions of ICAR:

    • Its primary mandate is to coordinate agricultural education and research in India and provide leadership in agriculture and allied sectors.
    • It is the apex body for coordinating, guiding and managing research and education in agriculture including horticulture, fisheries and animal sciences in the entire country.

    Structure and Organization:

    • ICAR operates under the Department of Agricultural Research and Education (DARE), Ministry of Agriculture and Farmers Welfare, Government of India.
    • It consists of a network of research institutes, national bureaus, project directorates, and agricultural universities across the country.
    • The council is governed by a Governing Body and an Executive Committee, which oversee its functioning and activities.
    • ICAR confers prestigious awards, such as: the Rafi Ahmed Kidwai Award, the Borlaug Award, and the Hari Om Ashram Trust Award, to recognize excellence in agricultural research and education.

    Significant feats achieved by ICAR:

    • Bio-fortified Coverage: In 2023-24, approximately 16 million hectares are cultivated with bio-fortified crop varieties.
    • Crops Mentioned: This includes wheat, rice, pearl millet, lentil, and mustard.
    • Climate Resilience: The deployment of climate-resilient technologies has boosted production, even in abnormal years.
    • Variety Release: From 2014-15 to 2023-24, ICAR has released 2,593 high-yielding varieties, including 2,177 climate-resilient and 150 bio-fortified varieties.

    What is the “One Scientist One Product” Scheme?

    • The “One Scientist One Product” initiative is a strategic research plan launched by the Indian Council of Agricultural Research (ICAR).
    • It aims to enhance agricultural productivity by assigning specific research targets to individual scientists within the organization in the next 5 years.

    Key Objectives of the Scheme:

    • Target-Oriented Research: Each scientist is given a specific target to develop a product. For example- seed variety, technology, research paper, or a conceptual model.
    • Avoiding Duplication: The initiative ensures that efforts are not duplicated by carefully mapping and assigning unique research targets to each scientist.
    • Regular Monitoring: Progress will be monitored every three months at the official level and twice a year by the researchers themselves.

    Implementation Details:

    • All 5,521 scientists of ICAR have been registered under this scheme.
    • At the beginning of each year, scientists must identify and inform about the product they aim to develop.
    • While the focus is on individual contributions, there will be instances where a product will be developed by a group of scientists.

    Long-Term Goals:

    • Product Development: The initiative is part of a broader plan to release 100 new seed varieties across various crops within the government’s 100-day plan.
    • Climate-Resilient Crops: A significant target is to increase the area under climate-resilient paddy seeds to 25% of the total kharif acreage, up from the current 15%.

    Announcement of New Crop Varieties

    • Event Details: ICAR will announce the release of 323 new crop varieties during a function in Delhi. The new releases include cereals, oilseeds, forage crops, and sugarcane.
    • Variety Breakdown: Among these, there are 289 climate-resilient varieties and 27 bio-fortified varieties.
    • Upcoming Initiatives: ICAR aims to develop 100 new seed varieties and 100 farm technologies within 100 days as part of a national 100-day action plan.

    Progress in Bio-fortification and Climate Resilience

    • ICAR reports significant progress in the adoption of bio-fortified crop varieties, with a total area of 16 million hectares under these varieties.
    • The organization emphasizes the success of its climate-resilient technologies, noting enhanced production even during years with abnormal weather conditions.

    PYQ:

    [2018] With reference to the Genetically Modified mustard (GM mustard) developed in India, consider the following statements:

    1. GM mustard has the genes of a soil bacterium that give the plant the property of pest-resistance to a wide variety of pests.
    2. GM mustard has the genes that allow the plant cross-pollination and hybridization.
    3. GM mustard has been developed jointly by the IARI and Punjab Agricultural University.

    Which of the statements given above is/are correct?

    (a) 1 and 3 only

    (b) 2 only

    (c) 2 and 3 only

    (d) 1, 2 and 3

  • Terrorism and Challenges Related To It

    Appointment of the new Additional National Security Advisor (ANSA)

    Why in the News?

    • A new Additional National Security Advisor (ANSA) was appointed on July 1, 2024, marking the first time this position has been filled. The ANSA will assist the National Security Advisor (NSA) in managing the country’s national security affairs.

    Recent Controversies about the NSA’s Role

    • Recent controversies involving R&AW and the Agniveer initiative have brought the NSA’s role back into focus.
    • Questions remain about the ideal background for the NSA and the prioritization of experience in internal versus external security.

    National Security Advisor (NSA):

    • The NSA is the senior official on the National Security Council of India.
    • The post was created on 19 November 1998 by the Government of Atal Bihari Vajpayee.
    • He/ She is also the chief adviser to the Prime Minister of India on national security policy and international affairs.
    • Ajit Doval is the current NSA, and has the same rank as a Union Cabinet Minister.
    • The NSA receives all intelligence (RAW, IB, NTRO, MI, DIA, NIA) reports and co-ordinates them to present before the Prime Minister.
    • The NSA serves at the discretion of the Prime Minister of India.

    About the National Security Council of India:

    • NSC is an executive government agency tasked with advising the Prime Minister’s Office on matters of national security and strategic interest.
    • The 3 tier structure of the NSC comprises:
    1. Strategic Policy Group (SPG),
    2. National Security Advisory Board (NSAB) and
    3. National Security Council Secretariat.
    • All aspects of national security are deliberated upon by the National Security Council (NSC), the apex body
    • Members: Ministers of Home Affairs, Defence, External Affairs, Finance and Deputy Chairman of the NITI Aayog.
    • The NSA is its Secretary.

    Changes in the National Security Architecture

    Previous Structure New Structure
    Additional National Security Advisor (ANSA) The position was consistently vacant New ANSA appointed for the first time
    NSA’s Role NSA had a more operational role NSA’s role is now more advisory, focusing on strategic policy and advisory outfits
    Reporting Structure CDS, service chiefs, and Union secretaries reported to NSA and their respective ministers CDS, service chiefs, and Union secretaries continue to report to NSA and their ministers; however, ANSA now acts as a gatekeeper
    Size of NSA’s Organization Smaller organization with no ANSA Larger organization with an ANSA and three deputy NSAs
    Daily Security Briefings Directly by NSA Unclear if briefings will be by NSA, ANSA, or both
    Communication Chain Direct communication between mid-level unit heads and NSA ANSA acts as an intermediary between mid-level unit heads and NSA, adding a bureaucratic layer
    Ministerial Reporting NSA interacted with Union ministers and Prime Minister Ministerial bosses also interact directly with respective secretaries, causing potential turf issues
    Speculations and Future Roles Speculations about the continuity and succession of the current NSA Ongoing speculations about the future role and potential succession by the newly appointed ANSA
    Internal Security Management NSA handled internal security along with other duties ANSA now specifically responsible for internal security management and threat analysis
    Overall Security Strategy NSA managed both strategic advisory and operational aspects Separation of strategic advisory role (NSA) and operational internal security role (ANSA)

    Issues with the re-structuring:

    • Bureaucratic Layering: The introduction of the ANSA adds an additional bureaucratic layer, potentially slowing down decision-making.
    • Turf Issues: Potential conflicts between the NSA and the Principal Secretary to the Prime Minister, especially regarding convening meetings.
    • Lack of clarity in Roles: Uncertainty about whether the NSA or ANSA will conduct daily security briefings, leading to possible communication confusion.
    • Ministerial Reporting Dynamics: Challenges for ministers in managing secretaries’ dual reporting lines to both the NSA and their respective ministers.
    • Operational Efficiency: The NSA’s shift to a more advisory role might affect the operational efficiency in handling immediate security threats.

    Future of the NSA

    • There is speculation about the future of the incumbent NSA, Ajit Doval, and whether his elevation is a precursor to retirement.
    • Questions arise about whether ANSA Rajinder Khanna will succeed Doval or if an outsider will be appointed.

    PYQ:

    [2021] Analyse the multidimensional challenges posed by external state and non-state actors, to the internal security of India. Also discuss measures required to be taken to combat these threats.

  • Innovations in Biotechnology and Medical Sciences

    100 years of Electroencephalography (EEG)

    Why in the News?

    This year marks the 100th anniversary of the first human electroencephalography (EEG) by German physiologist Hans Berger.

    Historical Development of EEG

    • The development of EEG started with Richard Caton in 1875, who first noticed electrical signals in the brains of animals.
    • His work was expanded by Adolf Beck and later by Vladimir Pravdich-Neminsky, who recorded the first EEG of a dog.
    • Hans Berger was the first to record these signals from a human brain in 1924.

    What is EEG?

    • EEG stands for electroencephalography. “Electro” means electricity, “encephalo” refers to the brain, and “graphy” means recording.
    • It tracks the electrical activity in the brain that happens when neurons, the brain’s cells, move tiny charged particles. 
    • This helps doctors tell if the brain is working normally or not.
    • Doctors use EEG to diagnose epilepsy, check how deep a person is under anesthesia, study sleep patterns, and even confirm if a person has passed away.

    Understanding Volume Conduction

    • Volume conduction explains how the brain’s electrical signals move through different layers like skin and bone to reach the electrodes on the scalp.
    • The signals that electrodes pick up need to be cleaned up from any distortions caused by these layers or other noises before doctors can read them accurately.

    How does an EEG Test Works?

    • Neurons interact with their surroundings and sometimes push ions around.
    • This movement creates waves of electrical activity.
    • Electrodes on the head detect these waves and measure how strong they are, which is then recorded as an EEG.
    • Setting up an EEG involves putting gel on the head and placing electrodes accurately, which can be affected by things like having thick hair.

    What EEG Can and Can’t Show?

    • Strengths: EEG is very good at catching fast changes in the brain’s electrical activity, which is helpful for immediate observations.
    • Limitations: It mainly detects signals from the surface of the brain and is better at picking up signals from certain types of cell parts than others.
      • Pinpointing exactly where the brain an activity started can be difficult.

    Cost and Accessibility

    • EEG is simple and affordable compared to other methods like MRI.
    • It’s portable, doesn’t use large equipment, and is safe.

    PYQ:

    [2015] With reference to ‘Near Field Communication (NFC) Technology’, which of the following statements is/are correct?

    1. It is a contactless communication technology that uses electromagnetic radio fields.

    2. NFC is designed for use by devices which can be at a distance of even a metre from each other.

    3. NFC can use encryption when sending sensitive information.

    Select the correct answer using the code given below:

    (a) 1 and 2 only

    (b) 3 only

    (c) 1 and 3 only

    (d) 1, 2 and 3

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